Monday, February 18, 2013

Design of a 13C magnetic resonance probe using a deuterated methoxy group as a long-lived hyperpolarization unit

Doura, T., et al., Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long-Lived Hyperpolarization Unit. Angew. Chem. Int. Ed., 2012. 51(40): p. 10114-10117.


How to live longer: A fully deuterated 13C methoxy group (13CD3O) is presented as a new long-lived hyperpolarization unit for designing a sensitive 13C magnetic resonance probe. By utilizing the unit, a hyperpolarized magnetic resonance probe for sensing hypochlorous acid was successfully designed.