Tuesday, January 17, 2012

BDPA: An Efficient Polarizing Agent for Fast Dissolution Dynamic Nuclear Polarization NMR Spectroscopy

Lumata, L., et al., BDPA: An Efficient Polarizing Agent for Fast Dissolution Dynamic Nuclear Polarization NMR Spectroscopy. Chemistry – A European Journal, 2011. 17(39): p. 10825-10827.

http://dx.doi.org/10.1002/chem.201102037

Teaching an old free radical new tricks: The stable free radical 1,3-bisdiphenylene-2-phenylallyl (BDPA) is an efficient polarizing agent in the dissolution dynamic nuclear polarization (DNP) of a variety of hydrophilic and hydrophobic compounds, such as tetramethylallene or [15N]choline. In addition, BDPA can be easily removed from the hyperpolarized solution by a simple mechanical filtration, when water is used for dissolution.